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Neoadjuvant Use of Oncolytic Herpes Virus G47Δ Enhances the Antitumor Efficacy of Radiofrequency Ablation

G47Δ is a triple-mutated oncolytic herpes simplex virus type 1 designed to induce antitumor immune responses efficiently. We examine the usefulness of G47Δ as a neoadjuvant therapy for radiofrequency ablation (RFA), a standard local treatment for certain cancers such as liver cancer, but remote recu...

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Detalles Bibliográficos
Autores principales: Yamada, Tomoharu, Tateishi, Ryosuke, Iwai, Miwako, Koike, Kazuhiko, Todo, Tomoki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7501409/
https://www.ncbi.nlm.nih.gov/pubmed/32995479
http://dx.doi.org/10.1016/j.omto.2020.08.010