Direct suppression of human islet dedifferentiation, progenitor genes, but not epithelial to mesenchymal transition by liraglutide

β-cell dedifferentiation has been accounted as one of the major mechanisms for β-cell failure; thus, is a cause to diabetes. We study direct impacts of liraglutide treatment on ex vivo human dedifferentiated islets, and its effects on genes important in endocrine function, progenitor states, and epi...

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Detalles Bibliográficos
Autores principales: Rattanaamnuaychai, Pimploy, Roshorm, Yaowaluck Maprang, Wilasrusmee, Chumpon, Proprom, Napaphat, Ongphiphadhanakul, Boonsong, Talchai, Shivatra Chutima
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7501427/
https://www.ncbi.nlm.nih.gov/pubmed/32995630
http://dx.doi.org/10.1016/j.heliyon.2020.e04951

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7501427/
https://www.ncbi.nlm.nih.gov/pubmed/32995630
http://dx.doi.org/10.1016/j.heliyon.2020.e04951

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