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Ablation of Stromal Cells with a Targeted Proapoptotic Peptide Suppresses Cancer Chemotherapy Resistance and Metastasis

Adipose stromal cells (ASCs) recruited by tumors contribute to the population of cancer-associated fibroblasts. ASCs have been reported to induce tumor growth and chemotherapy resistance. The effect of ASCs on metastasis has not been explored. Here, we investigated the role of ASCs in cancer aggress...

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Detalles Bibliográficos
Autores principales: Su, Fei, Wang, Xiaoping, Pearson, Troy, Lee, Jangsoon, Krishnamurthy, Savitri, Ueno, Naoto T., Kolonin, Mikhail G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7501461/
https://www.ncbi.nlm.nih.gov/pubmed/32995482
http://dx.doi.org/10.1016/j.omto.2020.08.012