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Abnormal Brain Development in Huntington’ Disease Is Recapitulated in the zQ175 Knock-In Mouse Model

Emerging cellular and molecular studies are providing compelling evidence that altered brain development contributes to the pathogenesis of Huntington’s disease (HD). There has been lacking longitudinal system-level data obtained from in vivo HD models supporting this hypothesis. Our human MRI study...

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Detalles Bibliográficos
Autores principales: Zhang, Chuangchuang, Wu, Qian, Liu, Hongshuai, Cheng, Liam, Hou, Zhipeng, Mori, Susumu, Hua, Jun, Ross, Christopher A, Zhang, Jiangyang, Nopoulos, Peggy C, Duan, Wenzhen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7501464/
https://www.ncbi.nlm.nih.gov/pubmed/32984817
http://dx.doi.org/10.1093/texcom/tgaa044