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Abnormal Brain Development in Huntington’ Disease Is Recapitulated in the zQ175 Knock-In Mouse Model
Emerging cellular and molecular studies are providing compelling evidence that altered brain development contributes to the pathogenesis of Huntington’s disease (HD). There has been lacking longitudinal system-level data obtained from in vivo HD models supporting this hypothesis. Our human MRI study...
Autores principales: | Zhang, Chuangchuang, Wu, Qian, Liu, Hongshuai, Cheng, Liam, Hou, Zhipeng, Mori, Susumu, Hua, Jun, Ross, Christopher A, Zhang, Jiangyang, Nopoulos, Peggy C, Duan, Wenzhen |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7501464/ https://www.ncbi.nlm.nih.gov/pubmed/32984817 http://dx.doi.org/10.1093/texcom/tgaa044 |
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