Cargando…

Rosuvastatin and simvastatin attenuate cisplatin-induced cardiotoxicity via disruption of endoplasmic reticulum stress-mediated apoptotic death in rats: targeting ER-Chaperone GRP78 and Calpain-1 pathways

Cisplatin (CP) is a powerful antineoplastic chemotherapeutic agent with broad-spectrum properties. Acute and cumulative cardiotoxicity are major limiting factors for CP therapy. Various pathogenic pathways have been suggested to CP-induced cardiotoxicity; oxidative damage, ER stress, and programmed...

Descripción completa

Detalles Bibliográficos
Autores principales:	Saleh, Dalia O., Mansour, Dina F., Mostafa, Rasha E.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2020
Materias:	Regular Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7501485/ https://www.ncbi.nlm.nih.gov/pubmed/32995293 http://dx.doi.org/10.1016/j.toxrep.2020.08.026

Ejemplares similares

The Endoplasmic Reticulum Chaperone GRP78/BiP Modulates Prion Propagation in vitro and in vivo
por: Park, Kyung-Won, et al.
Publicado: (2017)

Endoplasmic Reticulum Stress-Associated Chaperones, Bip/GRP78 and Calnexin are Overexpressed in Keratocystic Odontogenic Tumours
por: Pavli, Maria, et al.
Publicado: (2014)

Endoplasmic reticulum chaperone GRP78 is involved in autophagy activation induced by ischemic preconditioning in neural cells
por: Zhang, Xiang-Yang, et al.
Publicado: (2015)

Endoplasmic reticulum chaperone GRP78 mediates cigarette smoke-induced necroptosis and injury in bronchial epithelium
por: Wang, Yong, et al.
Publicado: (2018)

XAF1 drives apoptotic switch of endoplasmic reticulum stress response through destabilization of GRP78 and CHIP
por: Lee, Kyung-Woo, et al.
Publicado: (2022)

Cadmium Induces the Expression of Grp78, an Endoplasmic Reticulum Molecular Chaperone, in LLC-PK1 Renal Epithelial Cells
por: Liu, Fang, et al.
Publicado: (2006)

Endoplasmic reticulum chaperone BiP/GRP78 knockdown leads to autophagy and cell death of arginine vasopressin neurons in mice
por: Kawaguchi, Yohei, et al.
Publicado: (2020)

The Endoplasmic Reticulum Chaperone GRP170: From Immunobiology to Cancer Therapeutics
por: Wang, Hongxia, et al.
Publicado: (2015)

Covalent inhibition of endoplasmic reticulum chaperone GRP78 disconnects the transduction of ER stress signals to inflammation and lipid accumulation in diet-induced obese mice
por: Luo, Dan, et al.
Publicado: (2022)

Asiatic Acid Induces Endoplasmic Reticulum Stress and Activates the Grp78/IRE1α/JNK and Calpain Pathways to Inhibit Tongue Cancer Growth
por: Li, Jialin, et al.
Publicado: (2021)

Lysozyme Mutants Accumulate in Cells while Associated at their N-terminal Alpha-domain with the Endoplasmic Reticulum Chaperone GRP78/BiP
por: Kamada, Yoshiki, et al.
Publicado: (2016)

Secretion of the endoplasmic reticulum stress protein, GRP78, into the BALF is increased in cigarette smokers
por: Aksoy, Mark O., et al.
Publicado: (2017)

The endoplasmic reticulum chaperone BiP is a closure-accelerating cochaperone of Grp94
por: Huang, Bin, et al.
Publicado: (2022)

Mild Endoplasmic Reticulum Stress Promotes Retinal Neovascularization via Induction of BiP/GRP78
por: Nakamura, Shinsuke, et al.
Publicado: (2013)

Regulation of the Endoplasmic Reticulum Stress by BIP/GRP78 is involved in Meiotic Maturation of Porcine Oocytes In Vitro
por: Park, Hyo-Jin, et al.
Publicado: (2017)

EGCG Enhances the Chemosensitivity of Colorectal Cancer to Irinotecan through GRP78-MediatedEndoplasmic Reticulum Stress
por: Wu, Wenbing, et al.
Publicado: (2022)

Vulnerability of The Male Reproductive System to SARS-CoV-2 Invasion: Potential Role for The Endoplasmic Reticulum Chaperone Grp78/HSPA5/BiP
por: Sadeghi, Niloofar, et al.
Publicado: (2022)

A novel pathogenic role of the ER chaperone GRP78/BiP in rheumatoid arthritis
por: Yoo, Seung-Ah, et al.
Publicado: (2012)

Clusterin Protects Hepatocellular Carcinoma Cells from Endoplasmic Reticulum Stress Induced Apoptosis through GRP78
por: Wang, Cun, et al.
Publicado: (2013)

Tunicamycin promotes metastasis through upregulating endoplasmic reticulum stress induced GRP78 expression in thyroid carcinoma
por: Zhao, Guohong, et al.
Publicado: (2020)

Effects of GRP78 on Endoplasmic Reticulum Stress and Inflammatory Response in Macrophages of Large Yellow Croaker (Larimichthys crocea)
por: Sun, Jie, et al.
Publicado: (2023)

Relevance of serum levels of the endoplasmic reticulum stress protein GRP78 (glucose-regulated protein 78 kDa) as biomarker in pulmonary diseases
por: Al Zaidi, Muntadher, et al.
Publicado: (2023)

Upregulation of serum and glucocorticoid-regulated kinase 1 (SGK1) ameliorates doxorubicin-induced cardiotoxic injury, apoptosis, inflammation and oxidative stress by suppressing glucose regulated protein 78 (GRP78)-mediated endoplasmic reticulum stress
por: Wang, Feng, et al.
Publicado: (2021)

Role of Prostate Apoptosis Response 4 in Translocation of GRP78 from the Endoplasmic Reticulum to the Cell Surface of Trophoblastic Cells
por: Cohen, Marie, et al.
Publicado: (2013)

Interaction between PSMD10 and GRP78 accelerates endoplasmic reticulum stress-mediated hepatic apoptosis induced by homocysteine
por: Xiao, Kun, et al.
Publicado: (2021)

The endoplasmic reticulum chaperone PfGRP170 is essential for asexual development and is linked to stress response in malaria parasites
por: Kudyba, Heather M., et al.
Publicado: (2019)

The chaperone GRP78 is a host auxiliary factor for SARS-CoV-2 and GRP78 depleting antibody blocks viral entry and infection
por: Carlos, Anthony J., et al.
Publicado: (2021)

CaMKII activation participates in doxorubicin cardiotoxicity and is attenuated by moderate GRP78 overexpression
por: Tscheschner, Henrike, et al.
Publicado: (2019)

ER chaperone GRP78/BiP translocates to the nucleus under stress and acts as a transcriptional regulator
por: Liu, Ze, et al.
Publicado: (2023)

Inhibiting lysine 353 oxidation of GRP78 by a hypochlorous probe targeting endoplasmic reticulum promotes autophagy in cancer cells
por: Ning, Junya, et al.
Publicado: (2019)

The Circulating GRP78/BiP Is a Marker of Metabolic Diseases and Atherosclerosis: Bringing Endoplasmic Reticulum Stress into the Clinical Scenario
por: Girona, Josefa, et al.
Publicado: (2019)

Levels of circulating GRP78 and CHOP in endoplasmic reticulum stress pathways in Chinese type 2 diabetic kidney disease patients
por: Ma, Ning, et al.
Publicado: (2021)

Expression of the Endoplasmic Reticulum Stress Marker GRP78 in the Normal Retina and Retinal Degeneration Induced by Blue LED Stimuli in Mice
por: Park, Yong Soo, et al.
Publicado: (2021)

miR-30d, miR-181a and miR-199a-5p cooperatively suppress the endoplasmic reticulum chaperone and signaling regulator GRP78 in cancer
por: Su, S-F, et al.
Publicado: (2013)

The Molecular Chaperone GRP78/BiP in the Development of Chemoresistance: Mechanism and Possible Treatment
por: Roller, Corinna, et al.
Publicado: (2013)

The stress-inducible molecular chaperone GRP78 as potential therapeutic target for coronavirus infection
por: Ha, Dat P., et al.
Publicado: (2020)

The neuroprotective potential of endoplasmic reticulum chaperones
por: McLaughlin, Todd, et al.
Publicado: (2015)

Hydrogen sulfide inhibits endoplasmic reticulum stress through the GRP78/mTOR pathway in rat chondrocytes subjected to oxidative stress
por: Wu, Jianjun, et al.
Publicado: (2021)

The diagnostic value of endoplasmic reticulum stress-related specific proteins GRP78 and CHOP in patients with sepsis: a diagnostic cohort study
por: Li, Fangfang, et al.
Publicado: (2022)

GRP78 inhibitor HA15 increases the effect of Bortezomib on eradicating multiple myeloma cells through triggering endoplasmic reticulum stress
por: Chen, Yirong, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_70nufl5k8jr12o3hitrramg027