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Phase II multicenter randomized controlled clinical trial on the efficacy of intra-articular injection of autologous bone marrow mesenchymal stem cells with platelet rich plasma for the treatment of knee osteoarthritis

BACKGROUND: Mesenchymal stromal cells are a safe and promising option to treat knee osteoarthritis as previously demonstrated in different clinical trials. However, their efficacy, optimal dose and addition of adjuvants must be determined. Here, we evaluated the clinical effects of a dose of 100 × 1...

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Detalles Bibliográficos
Autores principales: Lamo-Espinosa, José María, Blanco, Juan F., Sánchez, Mikel, Moreno, Victoria, Granero-Moltó, Froilán, Sánchez-Guijo, Fermín, Crespo-Cullel, Íñigo, Mora, Gonzalo, San Vicente, Diego Delgado, Pompei-Fernández, Orlando, Aquerreta, Jesús Dámaso, Núñez-Córdoba, Jorge María, Vitoria Sola, María, Valentí-Azcárate, Andrés, Andreu, Enrique J., del Consuelo del Cañizo, María, Valentí-Nin, Juan Ramón, Prósper, Felipe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7501623/
https://www.ncbi.nlm.nih.gov/pubmed/32948200
http://dx.doi.org/10.1186/s12967-020-02530-6