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GMP-grade neural progenitor derivation and differentiation from clinical-grade human embryonic stem cells

BACKGROUND: A major challenge for the clinical use of human pluripotent stem cells is the development of safe, robust and controlled differentiation protocols. Adaptation of research protocols using reagents designated as research-only to those which are suitable for clinical use, often referred to...

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Detalles Bibliográficos
Autores principales: Vitillo, Loriana, Durance, Catherine, Hewitt, Zoe, Moore, Harry, Smith, Austin, Vallier, Ludovic
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7501686/
https://www.ncbi.nlm.nih.gov/pubmed/32948237
http://dx.doi.org/10.1186/s13287-020-01915-0