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Protective effects of DPP-4 inhibitor on podocyte injury in glomerular diseases

BACKGROUND: Dipeptidyl peptidase-4 (DPP-4) is a serine protease that inhibits the degradation of glucagon-like peptide 1. DPP-4 inhibitors are used worldwide to treat type 2 diabetes mellitus and were recently shown to have pleiotropic effects such as anti-oxidant, anti-inflammatory, and anti-fibrot...

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Detalles Bibliográficos
Autores principales: Kubo, Ayano, Hidaka, Teruo, Nakayama, Maiko, Sasaki, Yu, Takagi, Miyuki, Suzuki, Hitoshi, Suzuki, Yusuke
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7501714/
https://www.ncbi.nlm.nih.gov/pubmed/32948146
http://dx.doi.org/10.1186/s12882-020-02060-9