Cargando…
Apoptotic stress induces Bax-dependent, caspase-independent redistribution of LINC complex nesprins
The canonical function of Bcl-2 family proteins is to regulate mitochondrial membrane integrity. In response to apoptotic signals the multi-domain pro-apoptotic proteins Bax and Bak are activated and perforate the mitochondrial outer membrane by a mechanism which is inhibited by their interaction wi...
| Autores principales: | , , , , , , , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2020
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7501853/ https://www.ncbi.nlm.nih.gov/pubmed/33024575 http://dx.doi.org/10.1038/s41420-020-00327-6 |