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A dietary anthocyanin cyanidin-3-O-glucoside binds to PPARs to regulate glucose metabolism and insulin sensitivity in mice

We demonstrate the mechanism by which C3G, a major dietary anthocyanin, regulates energy metabolism and insulin sensitivity. Oral administration of C3G reduced hepatic and plasma triglyceride levels, adiposity, and improved glucose tolerance in mice fed high-fat diet. Hepatic metabolomic analysis re...

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Detalles Bibliográficos
Autores principales: Jia, Yaoyao, Wu, Chunyan, Kim, Young-Suk, Yang, Seung Ok, Kim, Yeonji, Kim, Ji-Sun, Jeong, Mi-Young, Lee, Ji Hae, Kim, Bobae, Lee, Soyoung, Oh, Hyun-Seok, Kim, Jia, So, Min-Young, Yoon, Ye Eun, Thach, Trung Thanh, Park, Tai Hyun, Lee, Sung-Joon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7501857/
https://www.ncbi.nlm.nih.gov/pubmed/32948821
http://dx.doi.org/10.1038/s42003-020-01231-6