Cargando…

The influence of choline treatment on behavioral and neurochemical autistic-like phenotype in Mthfr-deficient mice

Imbalanced one carbon metabolism and aberrant autophagy is robustly reported in patients with autism. Polymorphism in the gene methylenetetrahydrofolate reductase (Mthfr), encoding for a key enzyme in this pathway is associated with an increased risk for autistic-spectrum-disorders (ASDs). Autistic-...

Descripción completa

Detalles Bibliográficos
Autores principales: Agam, Galila, Taylor, Zoe, Vainer, Ella, Golan, Hava M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7501861/
https://www.ncbi.nlm.nih.gov/pubmed/32948746
http://dx.doi.org/10.1038/s41398-020-01002-1