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The influence of choline treatment on behavioral and neurochemical autistic-like phenotype in Mthfr-deficient mice
Imbalanced one carbon metabolism and aberrant autophagy is robustly reported in patients with autism. Polymorphism in the gene methylenetetrahydrofolate reductase (Mthfr), encoding for a key enzyme in this pathway is associated with an increased risk for autistic-spectrum-disorders (ASDs). Autistic-...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7501861/ https://www.ncbi.nlm.nih.gov/pubmed/32948746 http://dx.doi.org/10.1038/s41398-020-01002-1 |