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Abnormal Activations of Super-Enhancers Enhance the Carcinogenicity in Lung Adenocarcinoma

BACKGROUND: Lung tumors and normal lung tissues show large differences in epigenetic modification which can affect the chromosome structure and expression of genes. However, the epigenetic reprogramming in lung adenocarcinoma remains unclear. METHODS AND RESULTS: With the bioinformatics analysis, we...

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Detalles Bibliográficos
Autores principales: Zhou, Jianlong, Wang, Dingxue, Tang, Dongxin, Huang, Wenhua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7501973/
https://www.ncbi.nlm.nih.gov/pubmed/32982443
http://dx.doi.org/10.2147/CMAR.S258497