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(+)-Clausenamide protects against drug-induced liver injury by inhibiting hepatocyte ferroptosis
Drug-induced liver injury is the major cause of acute liver failure. However, the underlying mechanisms seem to be multifaceted and remain poorly understood, resulting in few effective therapies. Here, we report a novel mechanism that contributes to acetaminophen-induced hepatotoxicity through the i...
Autores principales: | , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7502081/ https://www.ncbi.nlm.nih.gov/pubmed/32951003 http://dx.doi.org/10.1038/s41419-020-02961-5 |