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(+)-Clausenamide protects against drug-induced liver injury by inhibiting hepatocyte ferroptosis

Drug-induced liver injury is the major cause of acute liver failure. However, the underlying mechanisms seem to be multifaceted and remain poorly understood, resulting in few effective therapies. Here, we report a novel mechanism that contributes to acetaminophen-induced hepatotoxicity through the i...

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Detalles Bibliográficos
Autores principales: Wang, Min, Liu, Chun-Yu, Wang, Tian, Yu, Hong-Min, Ouyang, Shu-Hua, Wu, Yan-Ping, Gong, Hai-Biao, Ma, Xiao-Hui, Jiao, Gen-Long, Fu, Lei-Lei, Wu, Qiong-Shi, Kurihara, Hiroshi, Li, Yi-Fang, Shen, Tao, He, Rong-Rong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7502081/
https://www.ncbi.nlm.nih.gov/pubmed/32951003
http://dx.doi.org/10.1038/s41419-020-02961-5