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Pharmacokinetic Effect of MDR Gene Polymorphism rs2032582 on the Therapeutic Response in Iraqi Patients with Acute Myeloid Leukemia

BACKGROUND: The main problem in treatment of leukemia patients is the chemotherapy resistance which is a main concern in recent years. The cause of chemotherapy drug resistance is related to MDR gene which is located on chromosome 7 (7q21-31) and it is mainly connected with energy-dependent efflux (...

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Detalles Bibliográficos
Autores principales: Abdulkareem, Rafid A., Rafaa, Tamadher Abbas, Jasim, Hamsa Ahmed, Suleiman, Ahmed Abdul Jabbar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Avicenna Research Institute 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7502164/
https://www.ncbi.nlm.nih.gov/pubmed/33014316