Vactosertib, a Novel, Orally Bioavailable Activin Receptor-Like Kinase 5 Inhibitor, Promotes Regression of Fibrotic Plaques in a Rat Model of Peyronie's Disease

PURPOSE: To examine the therapeutic effect of Vactosertib, a small molecule inhibitor of transforming growth factor-β (TGF-β) type I receptor (activin receptor-like kinase-5, ALK5), in an experimental model of Peyronie's disease (PD) and determining anti-fibrotic mechanisms of Vactosertib in pr...

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Detalles Bibliográficos
Autores principales: Song, Kang-Moon, Chung, Doo Yong, Choi, Min Ji, Ghatak, Kalyan, Minh, Nguyen Nhat, Limanjaya, Anita, Kwon, Mi-Hye, Ock, Jiyeon, Yin, Guo Nan, Kim, Dae-Kee, Ryu, Ji-Kan, Suh, Jun-Kyu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Society for Sexual Medicine and Andrology 2020
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7502315/
https://www.ncbi.nlm.nih.gov/pubmed/31496148
http://dx.doi.org/10.5534/wjmh.190071

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7502315/
https://www.ncbi.nlm.nih.gov/pubmed/31496148
http://dx.doi.org/10.5534/wjmh.190071

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