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Vactosertib, a Novel, Orally Bioavailable Activin Receptor-Like Kinase 5 Inhibitor, Promotes Regression of Fibrotic Plaques in a Rat Model of Peyronie's Disease
PURPOSE: To examine the therapeutic effect of Vactosertib, a small molecule inhibitor of transforming growth factor-β (TGF-β) type I receptor (activin receptor-like kinase-5, ALK5), in an experimental model of Peyronie's disease (PD) and determining anti-fibrotic mechanisms of Vactosertib in pr...
Autores principales: | Song, Kang-Moon, Chung, Doo Yong, Choi, Min Ji, Ghatak, Kalyan, Minh, Nguyen Nhat, Limanjaya, Anita, Kwon, Mi-Hye, Ock, Jiyeon, Yin, Guo Nan, Kim, Dae-Kee, Ryu, Ji-Kan, Suh, Jun-Kyu |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Korean Society for Sexual Medicine and Andrology
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7502315/ https://www.ncbi.nlm.nih.gov/pubmed/31496148 http://dx.doi.org/10.5534/wjmh.190071 |
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