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Deletion of NoxO1 limits atherosclerosis development in female mice

OBJECTIVE: Oxidative stress is a risk factor for atherosclerosis. NADPH oxidases of the Nox family produce ROS but their contribution to atherosclerosis development is less clear. Nox2 promotes and Nox4 rather limits atherosclerosis. Although Nox1 with its cytosolic co-factors are largely expressed...

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Detalles Bibliográficos
Autores principales: Buchmann, Giulia K., Schürmann, Christoph, Warwick, Tim, Schulz, Marcel H., Spaeth, Manuela, Müller, Oliver J., Schröder, Katrin, Jo, Hanjoong, Weissmann, Norbert, Brandes, Ralf P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7502371/
https://www.ncbi.nlm.nih.gov/pubmed/32949971
http://dx.doi.org/10.1016/j.redox.2020.101713