Cargando…

Deletion of NoxO1 limits atherosclerosis development in female mice

OBJECTIVE: Oxidative stress is a risk factor for atherosclerosis. NADPH oxidases of the Nox family produce ROS but their contribution to atherosclerosis development is less clear. Nox2 promotes and Nox4 rather limits atherosclerosis. Although Nox1 with its cytosolic co-factors are largely expressed...

Descripción completa

Detalles Bibliográficos
Autores principales:	Buchmann, Giulia K., Schürmann, Christoph, Warwick, Tim, Schulz, Marcel H., Spaeth, Manuela, Müller, Oliver J., Schröder, Katrin, Jo, Hanjoong, Weissmann, Norbert, Brandes, Ralf P.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2020
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7502371/ https://www.ncbi.nlm.nih.gov/pubmed/32949971 http://dx.doi.org/10.1016/j.redox.2020.101713

Ejemplares similares

NoxO1 Knockout Promotes Longevity in Mice
por: Schader, Tim, et al.
Publicado: (2020)

The NADPH organizers NoxO1 and p47phox are both mediators of diabetes-induced vascular dysfunction in mice
por: Rezende, Flávia, et al.
Publicado: (2017)

NoxO1 Controls Proliferation of Colon Epithelial Cells
por: Moll, Franziska, et al.
Publicado: (2018)

The hydrogen-peroxide producing NADPH oxidase 4 does not limit neointima development after vascular injury in mice
por: Buchmann, Giulia K., et al.
Publicado: (2021)

CRISPR/Cas9-mediated knockout of p22phox leads to loss of Nox1 and Nox4, but not Nox5 activity
por: Prior, Kim-Kristin, et al.
Publicado: (2016)

Overexpression of a Novel Noxo1 Mutant Increases Ros Production and Noxo1 Relocalisation
por: Benssouina, Fatima-Zahra, et al.
Publicado: (2023)

Knock out of the NADPH oxidase Nox4 has no impact on life span in mice
por: Rezende, Flavia, et al.
Publicado: (2016)

Regulation of NOXO1 Activity through Reversible Interactions with p22(phox) and NOXA1
por: Dutta, Sujit, et al.
Publicado: (2010)

Nox4 promotes endothelial differentiation through chromatin remodeling
por: Hahner, F., et al.
Publicado: (2022)

Micro-CT Technique Is Well Suited for Documentation of Remodeling Processes in Murine Carotid Arteries
por: Schürmann, Christoph, et al.
Publicado: (2015)

Genetic deletion of Nox4 enhances cancerogen-induced formation of solid tumors
por: Helfinger, Valeska, et al.
Publicado: (2021)

The flagellin-TLR5-Nox4 axis promotes the migration of smooth muscle cells in atherosclerosis
por: Kim, Jinoh, et al.
Publicado: (2019)

The Endoplasmic Reticulum Chaperone Calnexin Is a NADPH Oxidase NOX4 Interacting Protein
por: Prior, Kim-Kristin, et al.
Publicado: (2016)

Acute injury to the mouse carotid artery provokes a distinct healing response
por: Warwick, Timothy, et al.
Publicado: (2023)

Nox4 Maintains Blood Pressure during Low Sodium Diet
por: Rezende, Flávia, et al.
Publicado: (2021)

Reactive Oxygen Species Differentially Modulate the Metabolic and Transcriptomic Response of Endothelial Cells
por: Müller, Niklas, et al.
Publicado: (2022)

Both cardiomyocyte and endothelial cell Nox4 mediate protection against hemodynamic overload-induced remodelling
por: Zhang, Min, et al.
Publicado: (2018)

Nuclear receptor activation shapes spatial genome organization essential for gene expression control: lessons learned from the vitamin D receptor
por: Warwick, Timothy, et al.
Publicado: (2022)

NOX4 Regulates CCR2 and CCL2 mRNA Stability in Alcoholic Liver Disease
por: Sasaki, Yu, et al.
Publicado: (2017)

3D Imaging and Quantitative Analysis of Vascular Networks: A Comparison of Ultramicroscopy and Micro-Computed Tomography
por: Epah, Jeremy, et al.
Publicado: (2018)

Flow-induced reprogramming of endothelial cells in atherosclerosis
por: Tamargo, Ian A., et al.
Publicado: (2023)

Cre-Recombinase Induces Apoptosis and Cell Death in Enterocyte Organoids
por: Moll, Franziska, et al.
Publicado: (2022)

Nox4 Is Dispensable for Exercise Induced Muscle Fibre Switch
por: Vogel, Juri, et al.
Publicado: (2015)

A hierarchical regulatory network analysis of the vitamin D induced transcriptome reveals novel regulators and complete VDR dependency in monocytes
por: Warwick, Timothy, et al.
Publicado: (2021)

Accelerated atherosclerosis development in C57Bl6 mice by overexpressing AAV-mediated PCSK9 and partial carotid ligation
por: Kumar, Sandeep, et al.
Publicado: (2017)

Redox Regulation Beyond ROS: Why ROS Should Not Be Measured as Often
por: Brandes, Ralf P., et al.
Publicado: (2018)

NADPH oxidase 4 (Nox4) deletion accelerates liver regeneration in mice
por: Herranz-Itúrbide, M., et al.
Publicado: (2020)

Endothelial deletion of the cytochrome P450 reductase leads to cardiac remodelling
por: Lopez, Melina, et al.
Publicado: (2022)

Context-specific effects of NOX4 inactivation in acute myeloid leukemia (AML)
por: Demircan, Muhammed Burak, et al.
Publicado: (2022)

Nox
por: Hettche, Thomas, 1964-
Publicado: (1996)

Myeloid-cell-specific deletion of inducible nitric oxide synthase protects against smoke-induced pulmonary hypertension in mice
por: Gredic, Marija, et al.
Publicado: (2022)

Computational Methods to Study DNA:DNA:RNA Triplex Formation by lncRNAs
por: Warwick, Timothy, et al.
Publicado: (2023)

Myeloid-specific deletion of NOX2 prevents the metabolic and neurologic consequences of high fat diet
por: Pepping, Jennifer K., et al.
Publicado: (2017)

Targeted redox inhibition of protein phosphatase 1 by Nox4 regulates eIF2α‐mediated stress signaling
por: Santos, Celio XC, et al.
Publicado: (2016)

Nox‐4 deletion reduces oxidative stress and injury by PKC‐α‐associated mechanisms in diabetic nephropathy
por: Thallas‐Bonke, Vicki, et al.
Publicado: (2014)

Mechanical forces regulate endothelial-to-mesenchymal transition and atherosclerosis via an Alk5-Shc mechanotransduction pathway
por: Mehta, Vedanta, et al.
Publicado: (2021)

Recent Progress in in vitro Models for Atherosclerosis Studies
por: Chen, Jun, et al.
Publicado: (2022)

Efficacy and limitations of senolysis in atherosclerosis
por: Garrido, Abel Martin, et al.
Publicado: (2021)

Differential contribution of Nox1, Nox2 and Nox4 to kidney vascular oxidative stress and endothelial dysfunction in obesity
por: Muñoz, Mercedes, et al.
Publicado: (2019)

Endothelial UCP2 Is a Mechanosensitive Suppressor of Atherosclerosis
por: Luo, Jiang-Yun, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_hh12vgu6qoj5f29qjkmog5b5b1