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Human Secretary Phospholipase A2 Mutations and Their Clinical Implications
Phospholipases A2 (PLA(2)s) belong to a superfamily of enzymes responsible for hydrolysis of the sn-2 fatty acids of membrane phospholipids to release arachidonic acid. PLA(2)s are the rate limiting enzyme for the downstream synthesis of prostaglandins and leukotrienes that are the main mediators of...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7502393/ https://www.ncbi.nlm.nih.gov/pubmed/32982370 http://dx.doi.org/10.2147/JIR.S269557 |