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Nanomicellar Lenalidomide–Fenretinide Combination Suppresses Tumor Growth in an MYCN Amplified Neuroblastoma Tumor

PURPOSE: In a previous study, we demonstrated that the combination of fenretinide with lenalidomide, administered by a novel nanomicellar formulation (FLM), provided a strong antitumor effect in a neuroblastoma TrkB-expressing tumor. In this study, we tested the nanomicellar combination in an MYCN a...

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Detalles Bibliográficos
Autores principales: Orienti, Isabella, Farruggia, Giovanna, Nguyen, Ferro, Guan, Peng, Calonghi, Natalia, Kolla, Venkatadri, Chorny, Michael, Brodeur, Garrett M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7502401/
https://www.ncbi.nlm.nih.gov/pubmed/32982239
http://dx.doi.org/10.2147/IJN.S262032