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Limited proliferation capacity of aorta intima resident macrophages requires monocyte recruitment for atherosclerotic plaque progression

Early atherosclerosis depends upon responses by immune cells resident in the intimal aortic wall. Specifically, the healthy intima is thought to be populated by vascular dendritic cells (DC) that, during hypercholesterolemia, initiate atherosclerosis by being the first to accumulate cholesterol. Whe...

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Detalles Bibliográficos
Autores principales: Williams, Jesse W., Zaitsev, Konstantin, Kim, Ki-Wook, Ivanov, Stoyan, Saunders, Brian T., Schrank, Patricia R., Kim, Kyeongdae, Elvington, Andrew, Kim, Seung Hyeon, Tucker, Christopher G., Wohltmann, Mary, Fife, Brian T., Epelman, Slava, Artyomov, Maxim N., Lavine, Kory J., Zinselmeyer, Bernd H., Choi, Jae-Hoon, Randolph, Gwendalyn J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7502558/
https://www.ncbi.nlm.nih.gov/pubmed/32895539
http://dx.doi.org/10.1038/s41590-020-0768-4