STAT3 modulates reprogramming efficiency of human somatic cells; insights from autosomal dominant Hyper IgE syndrome caused by STAT3 mutations

Human induced pluripotent stem cell (iPSC) technology has opened exciting opportunities for stem-cell-based therapy. However, its wide adoption is precluded by several challenges including low reprogramming efficiency and potential for malignant transformation. Better understanding of the molecular...

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Detalles Bibliográficos
Autores principales: Yu, Zhen, Dmitrieva, Natalia I., Walts, Avram D., Jin, Hui, Liu, Yangtengyu, Ping, Xianfeng, Ferrante, Elisa A., Qiu, Lugui, Holland, Steven M., Freeman, Alexandra F., Chen, Guibin, Boehm, Manfred
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7502598/
https://www.ncbi.nlm.nih.gov/pubmed/32580970
http://dx.doi.org/10.1242/bio.052662

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7502598/
https://www.ncbi.nlm.nih.gov/pubmed/32580970
http://dx.doi.org/10.1242/bio.052662

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