A targeted reactivation of latent HIV-1 using an activator vector in patient samples from acute infection

BACKGROUND: During combined anti-retroviral treatment, a latent HIV reservoir persists within resting memory CD4 T cells that initiates viral recrudescence upon treatment interruption. Strategies for HIV-1 cure have largely focused on latency reversing agents (LRAs) capable of reactivating and elimi...

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Detalles Bibliográficos
Autores principales: Mann, Jamie F.S., Pankrac, Joshua, Klein, Katja, McKay, Paul F., King, Deborah F.L., Gibson, Richard, Wijewardhana, Chanuka N., Pawa, Rahul, Meyerowitz, Jodi, Gao, Yong, Canaday, David H., Avino, Mariano, Poon, Art F.Y., Foster, Caroline, Fidler, Sarah, Shattock, Robin J., Arts, Eric J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7502668/
https://www.ncbi.nlm.nih.gov/pubmed/32654992
http://dx.doi.org/10.1016/j.ebiom.2020.102853

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7502668/
https://www.ncbi.nlm.nih.gov/pubmed/32654992
http://dx.doi.org/10.1016/j.ebiom.2020.102853

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