Targeting a bacterial DNABII protein with a chimeric peptide immunogen or humanised monoclonal antibody to prevent or treat recalcitrant biofilm-mediated infections

BACKGROUND: Chronic and recurrent bacterial diseases are recalcitrant to treatment due to the ability of the causative agents to establish biofilms, thus development of means to prevent or resolve these structures are greatly needed. Our approach targets the DNABII family of bacterial DNA-binding pr...

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Detalles Bibliográficos
Autores principales: Novotny, Laura A., Goodman, Steven D., Bakaletz, Lauren O.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7502671/
https://www.ncbi.nlm.nih.gov/pubmed/32651162
http://dx.doi.org/10.1016/j.ebiom.2020.102867

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7502671/
https://www.ncbi.nlm.nih.gov/pubmed/32651162
http://dx.doi.org/10.1016/j.ebiom.2020.102867

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