Hyperlipidaemia and IFNgamma/TNFalpha Synergism are associated with cholesterol crystal formation in Endothelial cells partly through modulation of Lysosomal pH and Cholesterol homeostasis

BACKGROUND: Inflammation plays an important role in the development of cardiovascular disease (CVD). Patients with chronic inflammation diseases have high levels of inflammation and early fatal myocardial infarction due to early, unstable coronary plaques. Cholesterol crystals (CC) play a key role i...

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Detalles Bibliográficos
Autores principales: Baumer, Yvonne, Dey, Amit K., Gutierrez-Huerta, Cristhian A., Khalil, Noor O., Sekine, Yusuke, Sanda, Gregory E., Zhuang, Jie, Saxena, Ankit, Stempinski, Erin, Elnabawi, Youssef A., Dagur, Pradeep K., Ng, Qimin, Teague, Heather L., Keel, Andrew, Rodante, Justin A., Boisvert, William A., Tsoi, Lam C., Gudjonsson, Johann E., Bleck, Christopher K.E., Chen, Marcus Y., Bluemke, David A., Gelfand, Joel M., Schwartz, Daniella M., Kruth, Howard S., Powell-Wiley, Tiffany M., Playford, Martin P., Mehta, Nehal N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7502673/
https://www.ncbi.nlm.nih.gov/pubmed/32646751
http://dx.doi.org/10.1016/j.ebiom.2020.102876

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7502673/
https://www.ncbi.nlm.nih.gov/pubmed/32646751
http://dx.doi.org/10.1016/j.ebiom.2020.102876

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