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Defining an amyloid link Between Parkinson’s disease and melanoma

An epidemiological connection exists between Parkinson’s disease (PD) and melanoma. α-Synuclein (α-syn), the hallmark pathological amyloid observed in PD, is also elevated in melanoma, where its expression is inversely correlated with melanin content. We present a hypothesis that there is an amyloid...

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Detalles Bibliográficos
Autores principales: Dean, Dexter N., Lee, Jennifer C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7502734/
https://www.ncbi.nlm.nih.gov/pubmed/32868414
http://dx.doi.org/10.1073/pnas.2009702117