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Multiplexed conditional genome editing with Cas12a in Drosophila

CRISPR-Cas genome engineering has revolutionized biomedical research by enabling targeted genome modification with unprecedented ease. In the popular model organism Drosophila melanogaster, gene editing has so far relied exclusively on the prototypical CRISPR nuclease Cas9. Additional CRISPR systems...

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Detalles Bibliográficos
Autores principales: Port, Fillip, Starostecka, Maja, Boutros, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7502738/
https://www.ncbi.nlm.nih.gov/pubmed/32843348
http://dx.doi.org/10.1073/pnas.2004655117