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Kinetic profiling of metabolic specialists demonstrates stability and consistency of in vivo enzyme turnover numbers
Enzyme turnover numbers (k(cat)s) are essential for a quantitative understanding of cells. Because k(cat)s are traditionally measured in low-throughput assays, they can be inconsistent, labor-intensive to obtain, and can miss in vivo effects. We use a data-driven approach to estimate in vivo k(cat)s...
| Autores principales: | , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
National Academy of Sciences
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7502767/ https://www.ncbi.nlm.nih.gov/pubmed/32873645 http://dx.doi.org/10.1073/pnas.2001562117 |