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Development of binary dispersions and nanocomposites of irbesartan with enhanced antihypertensive activity

[Image: see text] Introduction: Irbesartan (IBS), an angiotensin II receptor (AT1 subtype) antagonist which blocks the vasoconstrictor and aldosterone-secreting effects of angiotensin II by selective binding to AT1 angiotensin II receptor. It belongs to BCS class II drug (low aqueous solubility and...

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Detalles Bibliográficos
Autores principales: Puri, Vivek, Nagpal, Manju, Sharma, Ameya, Thakur, Gurjeet Singh, Singh, Manjinder, Aggarwal, Geeta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Tabriz University of Medical Sciences 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7502911/
https://www.ncbi.nlm.nih.gov/pubmed/32983943
http://dx.doi.org/10.34172/bi.2020.34