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Development of binary dispersions and nanocomposites of irbesartan with enhanced antihypertensive activity
[Image: see text] Introduction: Irbesartan (IBS), an angiotensin II receptor (AT1 subtype) antagonist which blocks the vasoconstrictor and aldosterone-secreting effects of angiotensin II by selective binding to AT1 angiotensin II receptor. It belongs to BCS class II drug (low aqueous solubility and...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Tabriz University of Medical Sciences
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7502911/ https://www.ncbi.nlm.nih.gov/pubmed/32983943 http://dx.doi.org/10.34172/bi.2020.34 |