Deferasirox, an iron-chelating agent, alleviates acute lung inflammation by inhibiting neutrophil activation and extracellular trap formation

OBJECTIVE: Reactive oxygen species (ROS) production by neutrophils induces pulmonary endothelial cell damage and results in acute lung injury (ALI). We previously reported that deferasirox (DFS), an iron-chelating agent, inhibits the ROS production and neutrophil extracellular trap (NET) formation i...

Descripción completa

Detalles Bibliográficos
Autores principales: Kono, Mari, Matsuhiroya, Shiori, Obuchi, Ayako, Takahashi, Takayuki, Imoto, Shion, Kawano, Seiji, Saigo, Katsuyasu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2020
Materias:
Pre-Clinical Research Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7503029/
https://www.ncbi.nlm.nih.gov/pubmed/32938287
http://dx.doi.org/10.1177/0300060520951015

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7503029/
https://www.ncbi.nlm.nih.gov/pubmed/32938287
http://dx.doi.org/10.1177/0300060520951015

Ejemplares similares