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TP53 p.Arg337His geographic distribution correlates with adrenocortical tumor occurrence
BACKGROUND: The p.Arg337His mutation of the TP53 is the most frequent germline missense variant associated with cancer described so far in this gene. It is mainly found in the South and Southeastern regions of Brazil, where it has been associated with a high incidence of pediatric adrenocortical (AC...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7503091/ https://www.ncbi.nlm.nih.gov/pubmed/32592449 http://dx.doi.org/10.1002/mgg3.1168 |