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Microglia Implicated in Tauopathy in the Striatum of Neurodegenerative Disease Patients from Genotype to Phenotype

We found interactions between dopamine and oxidative damage in the striatum involved in advanced neurodegeneration, which probably change the microglial phenotype. We observed possible microglia dystrophy in the striatum of neurodegenerative brains. To investigate the interactions between oxidative...

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Detalles Bibliográficos
Autores principales: Li, Huifangjie, Knight, William C., Yang, Pengfei, Guo, Yingqiu, Perlmutter, Joel S., Morris, John C., Bateman, Randall J., Benzinger, Tammie L. S., Xu, Jinbin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7503242/
https://www.ncbi.nlm.nih.gov/pubmed/32842621
http://dx.doi.org/10.3390/ijms21176047