Modulation of the Paracrine Kynurenic System in Bone as a New Regulator of Osteoblastogenesis and Bone Mineral Status in an Animal Model of Chronic Kidney Disease Treated with LP533401

An increase in the peripheral synthesis of serotonin and kynurenine, observed during the chronic kidney disease (CKD) course, is negatively associated with bone health. Serotonin and kynurenine are connected by the common precursor, tryptophan. LP533401 is an inhibitor of peripheral serotonin synthe...

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Detalles Bibliográficos
Autores principales: Mor, Adrian, Pawlak, Krystyna, Kalaska, Bartlomiej, Domaniewski, Tomasz, Sieklucka, Beata, Zieminska, Marta, Cylwik, Bogdan, Pawlak, Dariusz
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7503245/
https://www.ncbi.nlm.nih.gov/pubmed/32825192
http://dx.doi.org/10.3390/ijms21175979

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7503245/
https://www.ncbi.nlm.nih.gov/pubmed/32825192
http://dx.doi.org/10.3390/ijms21175979

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