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The Structure of Clostridioides difficile SecA2 ATPase Exposes Regions Responsible for Differential Target Recognition of the SecA1 and SecA2-Dependent Systems

SecA protein is a major component of the general bacterial secretory system. It is an ATPase that couples nucleotide hydrolysis to protein translocation. In some Gram-positive pathogens, a second paralogue, SecA2, exports a different set of substrates, usually virulence factors. To identify SecA2 fe...

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Detalles Bibliográficos
Autores principales: Lindič, Nataša, Loboda, Jure, Usenik, Aleksandra, Vidmar, Robert, Turk, Dušan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7503281/
https://www.ncbi.nlm.nih.gov/pubmed/32858965
http://dx.doi.org/10.3390/ijms21176153