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Proteostasis and Proteotoxicity in the Network Medicine Era

Neurodegenerative proteinopathies are complex diseases that share some pathogenetic processes. One of these is the failure of the proteostasis network (PN), which includes all components involved in the synthesis, folding, and degradation of proteins, thus leading to the aberrant accumulation of tox...

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Detalles Bibliográficos
Autores principales: Lualdi, Marta, Alberio, Tiziana, Fasano, Mauro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7503343/
https://www.ncbi.nlm.nih.gov/pubmed/32899160
http://dx.doi.org/10.3390/ijms21176405