Prediction of Premature Termination Codon Suppressing Compounds for Treatment of Duchenne Muscular Dystrophy Using Machine Learning

A significant percentage of Duchenne muscular dystrophy (DMD) cases are caused by premature termination codon (PTC) mutations in the dystrophin gene, leading to the production of a truncated, non-functional dystrophin polypeptide. PTC-suppressing compounds (PTCSC) have been developed in order to res...

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Detalles Bibliográficos
Autores principales: Wang, Kate, Romm, Eden L., Kouznetsova, Valentina L., Tsigelny, Igor F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7503396/
https://www.ncbi.nlm.nih.gov/pubmed/32858918
http://dx.doi.org/10.3390/molecules25173886

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7503396/
https://www.ncbi.nlm.nih.gov/pubmed/32858918
http://dx.doi.org/10.3390/molecules25173886

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