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The Effect of Dysfunctional Ubiquitin Enzymes in the Pathogenesis of Most Common Diseases

Ubiquitination is a multi-step enzymatic process that involves the marking of a substrate protein by bonding a ubiquitin and protein for proteolytic degradation mainly via the ubiquitin–proteasome system (UPS). The process is regulated by three main types of enzymes, namely ubiquitin-activating enzy...

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Detalles Bibliográficos
Autores principales: Celebi, Gizem, Kesim, Hale, Ozer, Ebru, Kutlu, Ozlem
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7503467/
https://www.ncbi.nlm.nih.gov/pubmed/32882786
http://dx.doi.org/10.3390/ijms21176335