Using a Simple Cellular Assay to Map NES Motifs in Cancer-Related Proteins, Gain Insight into CRM1-Mediated NES Export, and Search for NES-Harboring Micropeptides

The nuclear export receptor CRM1 (XPO1) recognizes and binds specific sequence motifs termed nuclear export signals (NESs) in cargo proteins. About 200 NES motifs have been identified, but over a thousand human proteins are potential CRM1 cargos, and most of their NESs remain to be identified. On th...

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Detalles Bibliográficos
Autores principales: Sendino, Maria, Omaetxebarria, Miren Josu, Prieto, Gorka, Rodriguez, Jose Antonio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7503480/
https://www.ncbi.nlm.nih.gov/pubmed/32882917
http://dx.doi.org/10.3390/ijms21176341

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7503480/
https://www.ncbi.nlm.nih.gov/pubmed/32882917
http://dx.doi.org/10.3390/ijms21176341

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