Hydride Abstraction as the Rate-Limiting Step of the Irreversible Inhibition of Monoamine Oxidase B by Rasagiline and Selegiline: A Computational Empirical Valence Bond Study

Monoamine oxidases (MAOs) catalyze the degradation of a very broad range of biogenic and dietary amines including many neurotransmitters in the brain, whose imbalance is extensively linked with the biochemical pathology of various neurological disorders, and are, accordingly, used as primary pharmac...

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Detalles Bibliográficos
Autores principales: Tandarić, Tana, Prah, Alja, Stare, Jernej, Mavri, Janez, Vianello, Robert
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7503497/
https://www.ncbi.nlm.nih.gov/pubmed/32858935
http://dx.doi.org/10.3390/ijms21176151

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7503497/
https://www.ncbi.nlm.nih.gov/pubmed/32858935
http://dx.doi.org/10.3390/ijms21176151

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