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Ternary Cu(II) Complex with GHK Peptide and Cis-Urocanic Acid as a Potential Physiologically Functional Copper Chelate

The tripeptide NH(2)–Gly–His–Lys–COOH (GHK), cis-urocanic acid (cis-UCA) and Cu(II) ions are physiological constituents of the human body and they co-occur (e.g., in the skin and the plasma). While GHK is known as Cu(II)-binding molecule, we found that urocanic acid also coordinates Cu(II) ions. Fur...

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Detalles Bibliográficos
Autores principales: Bossak-Ahmad, Karolina, Wiśniewska, Marta D., Bal, Wojciech, Drew, Simon C., Frączyk, Tomasz
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7503498/
https://www.ncbi.nlm.nih.gov/pubmed/32867146
http://dx.doi.org/10.3390/ijms21176190