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Normoxic Tumour Extracellular Vesicles Modulate the Response of Hypoxic Cancer and Stromal Cells to Doxorubicin In Vitro

Extracellular vesicles (EV) secreted in the tumour microenvironment (TME) are emerging as major antagonists of anticancer therapies by orchestrating the therapeutic outcome through altering the behaviour of recipient cells. Recent evidence suggested that chemotherapeutic drugs could be responsible f...

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Detalles Bibliográficos
Autores principales: Patras, Laura, Fens, Marcel H. A. M., Vader, Pieter, Barendrecht, Arjan, Sesarman, Alina, Banciu, Manuela, Schiffelers, Raymond
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7503554/
https://www.ncbi.nlm.nih.gov/pubmed/32824972
http://dx.doi.org/10.3390/ijms21175951