CRISPR-Cas9 DNA Base-Editing and Prime-Editing

Many genetic diseases and undesirable traits are due to base-pair alterations in genomic DNA. Base-editing, the newest evolution of clustered regularly interspaced short palindromic repeats (CRISPR)-Cas-based technologies, can directly install point-mutations in cellular DNA without inducing a doubl...

Descripción completa

Detalles Bibliográficos
Autores principales: Kantor, Ariel, McClements, Michelle E., MacLaren, Robert E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7503568/
https://www.ncbi.nlm.nih.gov/pubmed/32872311
http://dx.doi.org/10.3390/ijms21176240

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7503568/
https://www.ncbi.nlm.nih.gov/pubmed/32872311
http://dx.doi.org/10.3390/ijms21176240

Ejemplares similares