A Split Luciferase Complementation Assay for the Quantification of β-Arrestin2 Recruitment to Dopamine D(2)-Like Receptors

Investigations on functional selectivity of GPCR ligands have become increasingly important to identify compounds with a potentially more beneficial side effect profile. In order to discriminate between individual signaling pathways, the determination of β-arrestin2 recruitment, in addition to G-pro...

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Detalles Bibliográficos
Autores principales: Forster, Lisa, Grätz, Lukas, Mönnich, Denise, Bernhardt, Günther, Pockes, Steffen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7503597/
https://www.ncbi.nlm.nih.gov/pubmed/32847148
http://dx.doi.org/10.3390/ijms21176103

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7503597/
https://www.ncbi.nlm.nih.gov/pubmed/32847148
http://dx.doi.org/10.3390/ijms21176103

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