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A Split Luciferase Complementation Assay for the Quantification of β-Arrestin2 Recruitment to Dopamine D(2)-Like Receptors
Investigations on functional selectivity of GPCR ligands have become increasingly important to identify compounds with a potentially more beneficial side effect profile. In order to discriminate between individual signaling pathways, the determination of β-arrestin2 recruitment, in addition to G-pro...
Autores principales: | Forster, Lisa, Grätz, Lukas, Mönnich, Denise, Bernhardt, Günther, Pockes, Steffen |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7503597/ https://www.ncbi.nlm.nih.gov/pubmed/32847148 http://dx.doi.org/10.3390/ijms21176103 |
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