Repurposing Quinacrine for Treatment of Malignant Mesothelioma: In-Vitro Therapeutic and Mechanistic Evaluation

Malignant mesothelioma (MM) is a rare type of cancer primarily affecting mesothelial cells lining the pleural cavity. In this study, we propose to repurpose quinacrine (QA), a widely approved anti-malarial drug, for Malignant Pleural Mesothelioma (MPM) treatment. QA demonstrates high degree of cytot...

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Detalles Bibliográficos
Autores principales: Kulkarni, Nishant S., Vaidya, Bhuvaneshwar, Parvathaneni, Vineela, Bhanja, Debarati, Gupta, Vivek
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7503636/
https://www.ncbi.nlm.nih.gov/pubmed/32878257
http://dx.doi.org/10.3390/ijms21176306

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7503636/
https://www.ncbi.nlm.nih.gov/pubmed/32878257
http://dx.doi.org/10.3390/ijms21176306

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