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Repurposing Quinacrine for Treatment of Malignant Mesothelioma: In-Vitro Therapeutic and Mechanistic Evaluation
Malignant mesothelioma (MM) is a rare type of cancer primarily affecting mesothelial cells lining the pleural cavity. In this study, we propose to repurpose quinacrine (QA), a widely approved anti-malarial drug, for Malignant Pleural Mesothelioma (MPM) treatment. QA demonstrates high degree of cytot...
Autores principales: | Kulkarni, Nishant S., Vaidya, Bhuvaneshwar, Parvathaneni, Vineela, Bhanja, Debarati, Gupta, Vivek |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7503636/ https://www.ncbi.nlm.nih.gov/pubmed/32878257 http://dx.doi.org/10.3390/ijms21176306 |
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